Effects of the single nucleotide polymorphism at MDM2 309 on breast cancer patients with/without BRCA1/2 mutations

<p>Abstract</p> <p>Background</p> <p>A germ line single nucleotide polymorphism (SNP) in the first intron of the gene encoding MDM2 at position 309, an important modulator of p53, has been described. BRCA1/2 mutation have been associated with increased rates of breast c...

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Bibliographic Details
Main Authors: Sharon Nir, Kadouri Luna, Mendelson Susan, Hamburger Tamar, Nechushtan Hovav, Pikarsky Eli, Peretz Tamar
Format: Article
Language:English
Published: BMC 2009-02-01
Series:BMC Cancer
Online Access:http://www.biomedcentral.com/1471-2407/9/60