Deletion of mouse FXR gene disturbs multiple neurotransmitter systems and alters neurobehavior

Deletion of mouse FXR gene disturbs multiple neurotransmitter systems and alters neurobehavior

Farnesoid X receptor (FXR) is a nuclear hormone receptor involved in bile acid synthesis and homeostasis. Dysfunction of FXR is involved in cholestasis and atherosclerosis. FXR is prevalent in liver, gallbladder, and intestine, but it is not yet clear whether it modulates neurobehavior. In the curre...

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Bibliographic Details
Main Authors: Fei eHuang, Tingting eWang, Yunyi eLan, Li eYang, Weihong ePan, Yonghui eZhu, Boyang eLv, Yuting eWei, Hailian eShi, Hui eWu, Beibei eZhang, Jie eWang, Xiaofeng eDuan, Zhibi eHu, Xiaojun eWu
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-03-01
Series:Frontiers in Behavioral Neuroscience
Subjects:
Memory
emotion
neurotransmission
neurotransmitter
Bile acid
Motor performance
Online Access:http://journal.frontiersin.org/Journal/10.3389/fnbeh.2015.00070/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fnbeh.2015.00070/full

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