Mitochondrial Mutations and Polymorphisms in Psychiatric Disorders

Mitochondrial Mutations and Polymorphisms in Psychiatric Disorders

Mitochondrial deficiencies with unknown causes have been observed in schizophrenia (SZ) and bipolar disorder (BD) in imaging and postmortem studies. Polymorphisms and somatic mutations in mitochondrial DNA (mtDNA) were investigated as potential causes with next generation sequencing of mtDNA (mtDNA-...

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Bibliographic Details
Main Authors: Adolfo eSequeira, Maureen eMartin, Brandi eRollins, Emily eMoon, William E Bunney, Fabio eMacciardi, Sara eLupoli, Erin eSmith, John eKelsoe, Christophe eMagnan, Mannis eVan Oven, Pierre eBaldi, Douglas eWallace, Marquis P Vawter
Format: Article
Language:English
Published: Frontiers Media S.A. 2012-06-01
Series:Frontiers in Genetics
Subjects:
Bipolar Disorder
Mitochondria
Schizophrenia
homoplasmy
common deletion
novel mutations
Online Access:http://journal.frontiersin.org/Journal/10.3389/fgene.2012.00103/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fgene.2012.00103/full

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