Engineered anopheles immunity to Plasmodium infection.

A causative agent of human malaria, Plasmodium falciparum, is transmitted by Anopheles mosquitoes. The malaria parasite is under intensive attack from the mosquito's innate immune system during its sporogonic development. We have used genetic engineering to create immune-enhanced Anopheles step...

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Bibliographic Details
Main Authors: Yuemei Dong, Suchismita Das, Chris Cirimotich, Jayme A Souza-Neto, Kyle J McLean, George Dimopoulos
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-12-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC3245315?pdf=render