Heterogeneity in malaria exposure and vaccine response: implications for the interpretation of vaccine efficacy trials

<p>Abstract</p> <p>Background</p> <p>Phase III trials of the malaria vaccine, RTS, S, are now underway across multiple sites of varying transmission intensity in Africa. Heterogeneity in exposure, vaccine response and waning of efficacy may bias estimates of vaccine eff...

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Bibliographic Details
Main Authors: Drakeley Chris J, Griffin Jamie T, White Michael T, Ghani Azra C
Format: Article
Language:English
Published: BMC 2010-03-01
Series:Malaria Journal
Online Access:http://www.malariajournal.com/content/9/1/82