Active trafficking of alpha 1 antitrypsin across the lung endothelium.

Active trafficking of alpha 1 antitrypsin across the lung endothelium.

The homeostatic lung protective effects of alpha-1 antitrypsin (A1AT) may require the transport of circulating proteinase inhibitor across an intact lung endothelial barrier. We hypothesized that uninjured pulmonary endothelial cells transport A1AT to lung epithelial cells. Purified human A1AT was r...

Full description

Bibliographic Details
Main Authors: Angelia D Lockett, Mary Beth Brown, Nieves Santos-Falcon, Natalia I Rush, Houssam Oueini, Amber J Oberle, Esther Bolanis, Miryam A Fragoso, Daniela N Petrusca, Karina A Serban, Kelly S Schweitzer, Robert G Presson, Michael Campos, Irina Petrache
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3990572?pdf=render

Internet

http://europepmc.org/articles/PMC3990572?pdf=render

Similar Items