Platelet hyaluronidase 2 enrichment in acute coronary syndromes: a conceivable role in monocyte-platelet aggregate formation

Platelet hyaluronidase 2 enrichment in acute coronary syndromes: a conceivable role in monocyte-platelet aggregate formation

Acute Coronary Syndromes (ACS) with plaque erosion display dysregulated hyaluronan metabolism, with increased hyaluronidase-2 (HYAL2) expression. However, the expression and the role of this enzyme on platelets has never been explored. We evaluated the platelet’s HYAL2 (pltHYAL2) levels on I) stable...

Full description

Bibliographic Details
Main Authors: Ramona Vinci, Daniela Pedicino, Alessia D’Aiello, Pellegrino Ciampi, Myriana Ponzo, Alice Bonanni, Giulio Russo, Rocco Antonio Montone, Massimo Massetti, Filippo Crea, Giovanna Liuzzo
Format: Article
Language:English
Published: Taylor & Francis Group 2021-01-01
Series:Journal of Enzyme Inhibition and Medicinal Chemistry
Subjects:
acute coronary syndromes
hyaluronic acid
hyaluronidase
platelets
personalised medicine
Online Access:http://dx.doi.org/10.1080/14756366.2021.1900159

Internet

http://dx.doi.org/10.1080/14756366.2021.1900159

Similar Items