Expression of an endotoxin-free S-layer/allergen fusion protein in gram-positive <it>Bacillus subtilis </it>1012 for the potential application as vaccines for immunotherapy of atopic allergy

Expression of an endotoxin-free S-layer/allergen fusion protein in gram-positive <it>Bacillus subtilis </it>1012 for the potential application as vaccines for immunotherapy of atopic allergy

<p>Abstract</p> <p>Background</p> <p>Genetic fusion of the major birch pollen allergen (Bet v1) to bacterial surface-(S)-layer proteins resulted in recombinant proteins exhibiting reduced allergenicity as well as immunomodulatory capacity. Thus, S-layer/allergen fusion...

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Bibliographic Details
Main Authors: Egelseer Eva, Bohle Barbara, Schumi Christian-Thomas, Ilk Nicola, Sleytr Uwe B
Format: Article
Language:English
Published: BMC 2011-02-01
Series:Microbial Cell Factories
Online Access:http://www.microbialcellfactories.com/content/10/1/6

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http://www.microbialcellfactories.com/content/10/1/6

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