Telomeres and Cell Senescence - Size Matters Not
Telomeres are protective structures present at the ends of linear chromosomes that are important in preventing genome instability. Telomeres shorten as a result of cellular replication, leading to a permanent cell cycle arrest, also known as replicative senescence. Senescent cells have been shown to...
Main Authors: | , |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2017-07-01
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Series: | EBioMedicine |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2352396417301238 |