Evaluation of recombinant MGL_1304 produced by Pichia pastoris for clinical application to sweat allergy

Evaluation of recombinant MGL_1304 produced by Pichia pastoris for clinical application to sweat allergy

Background: We previously identified MGL_1304 secreted by Malassezia globosa as a sweat antigen for patients with atopic dermatitis (AD) and cholinergic urticaria (ChU). However, purifying native MGL_1304 from human sweat or culture supernatant of M. globosa (sup-MGL_1304) is costly and time-consumi...

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Bibliographic Details
Main Authors: Takanobu Kan, Takaaki Hiragun, Kaori Ishii, Makiko Hiragun, Yuhki Yanase, Akio Tanaka, Michihiro Hide
Format: Article
Language:English
Published: Elsevier 2015-07-01
Series:Allergology International
Subjects:
HRT
MGL_1304
Pichia pastoris
Sweat allergy
β-hexosaminidase release
Online Access:http://www.sciencedirect.com/science/article/pii/S1323893015000933

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http://www.sciencedirect.com/science/article/pii/S1323893015000933

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