Investigation of factors that cause insulin precipitation and/or amyloid formation in insulin formulations

Investigation of factors that cause insulin precipitation and/or amyloid formation in insulin formulations

Abstract Background Multiple daily subcutaneous injections (MDSIs) are mainly used for formulating an insulin therapy for diabetic patients; however, they also cause insulin-derived amyloidosis (IDA) and lead to poor glycemic control. In addition, for the continuous subcutaneous insulin infusion sys...

Full description

Bibliographic Details
Main Authors: Yui Ohno, Tomohiro Seki, Yu Kojima, Ryotaro Miki, Yuya Egawa, Osamu Hosoya, Keizo Kasono, Toshinobu Seki
Format: Article
Language:English
Published: BMC 2019-10-01
Series:Journal of Pharmaceutical Health Care and Sciences
Subjects:
Insulin
Insulin analog
Insulin pump
Multiple daily subcutaneous injections
Continuous subcutaneous insulin infusion
Intravenous solution
Online Access:http://link.springer.com/article/10.1186/s40780-019-0151-5

Internet

http://link.springer.com/article/10.1186/s40780-019-0151-5

Similar Items