Ethanol causes and lithium prevents neuroapoptosis and suppression of pERK in the infant mouse brain

Transient exposure of immature animals during the brain growth spurt period to ethanol triggers neuroapoptosis in the developing brain. Here we report that lithium, when administered in a single, well-tolerated dose to infant mice, suppresses spontaneous neuroapoptosis that occurs naturally in the d...

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Bibliographic Details
Main Authors: Chainllie Young, Megan M.W. Straiko, Stephen A. Johnson, Catherine Creeley, John W. Olney
Format: Article
Language:English
Published: Elsevier 2008-09-01
Series:Neurobiology of Disease
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996108001034