T-helper Cell Type-1 Transcription Factor T-Bet Is Down-regulated in Type 1 Diabetes

T cells have been identified as key players in the pathogenesis of type 1 diabetes. However, the exact role of T-cell subpopulations in this pathway is presently unknown. The purpose of this study was to assess the expression pattern of two lineage-specifying transcription factors GATA-3 and T-bet,...

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Bibliographic Details
Main Authors: Hajar Vaseghi, Mohammad Hossein Sanati, Zohreh Jadali
Format: Article
Language:English
Published: Tehran University of Medical Sciences 2016-10-01
Series:Iranian Journal of Allergy, Asthma and Immunology
Subjects:
Online Access:https://ijaai.tums.ac.ir/index.php/ijaai/article/view/734