Identifying Effective Antiviral Drugs Against SARS-CoV-2 by Drug Repositioning Through Virus-Drug Association Prediction

Identifying Effective Antiviral Drugs Against SARS-CoV-2 by Drug Repositioning Through Virus-Drug Association Prediction

A new coronavirus called SARS-CoV-2 is rapidly spreading around the world. Over 16,558,289 infected cases with 656,093 deaths have been reported by July 29th, 2020, and it is urgent to identify effective antiviral treatment. In this study, potential antiviral drugs against SARS-CoV-2 were identified...

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Bibliographic Details
Main Authors: Lihong Peng, Xiongfei Tian, Ling Shen, Ming Kuang, Tianbao Li, Geng Tian, Jialiang Yang, Liqian Zhou
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-09-01
Series:Frontiers in Genetics
Subjects:
SARS-CoV-2
antiviral drugs
drug repositioning
virus-drug association
regularized least square
bipartite local model
Online Access:https://www.frontiersin.org/article/10.3389/fgene.2020.577387/full

Internet

https://www.frontiersin.org/article/10.3389/fgene.2020.577387/full

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