A Comprehensive Review of Autophagy and Its Various Roles in Infectious, Non-Infectious, and Lifestyle Diseases: Current Knowledge and Prospects for Disease Prevention, Novel Drug Design, and Therapy

A Comprehensive Review of Autophagy and Its Various Roles in Infectious, Non-Infectious, and Lifestyle Diseases: Current Knowledge and Prospects for Disease Prevention, Novel Drug Design, and Therapy

Autophagy (self-eating) is a conserved cellular degradation process that plays important roles in maintaining homeostasis and preventing nutritional, metabolic, and infection-mediated stresses. Autophagy dysfunction can have various pathological consequences, including tumor progression, pathogen hy...

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Bibliographic Details
Main Authors: Rekha Khandia, Maryam Dadar, Ashok Munjal, Kuldeep Dhama, Kumaragurubaran Karthik, Ruchi Tiwari, Mohd. Iqbal Yatoo, Hafiz M.N. Iqbal, Karam Pal Singh, Sunil K. Joshi, Wanpen Chaicumpa
Format: Article
Language:English
Published: MDPI AG 2019-07-01
Series:Cells
Subjects:
autophagy mechanism
autophagy-associated diseases
macroautophagy
chaperone-mediated autophagy
apoptosis
necroptosis
necrosis
iron homeostasis
autophagy inhibition
AKT/mTOR signaling pathway
autosis
Online Access:https://www.mdpi.com/2073-4409/8/7/674

Internet

https://www.mdpi.com/2073-4409/8/7/674

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