Cervical cancer stem cells manifest radioresistance: Association with upregulated AP-1 activity
Abstract Transcription factor AP-1 plays a central role in HPV-mediated cervical carcinogenesis. AP-1 has also been implicated in chemo-radio-resistance but the mechanism(s) remained unexplored. In the present study, cervical cancer stem-like cells (CaCxSLCs) isolated and enriched from cervical canc...
Main Authors: | Abhishek Tyagi, Kanchan Vishnoi, Harsimrut Kaur, Yogesh Srivastava, Bal Gangadhar Roy, Bhudev C. Das, Alok C. Bharti |
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Format: | Article |
Language: | English |
Published: |
Nature Publishing Group
2017-07-01
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Series: | Scientific Reports |
Online Access: | https://doi.org/10.1038/s41598-017-05162-x |
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