Cervical cancer stem cells manifest radioresistance: Association with upregulated AP-1 activity

Abstract Transcription factor AP-1 plays a central role in HPV-mediated cervical carcinogenesis. AP-1 has also been implicated in chemo-radio-resistance but the mechanism(s) remained unexplored. In the present study, cervical cancer stem-like cells (CaCxSLCs) isolated and enriched from cervical canc...

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Bibliographic Details
Main Authors: Abhishek Tyagi, Kanchan Vishnoi, Harsimrut Kaur, Yogesh Srivastava, Bal Gangadhar Roy, Bhudev C. Das, Alok C. Bharti
Format: Article
Language:English
Published: Nature Publishing Group 2017-07-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-017-05162-x