Putative roles of SLC7A5 (LAT1) transporter in pain

Putative roles of SLC7A5 (LAT1) transporter in pain

Large amino acid transporter 1 (LAT1), also known as SLC7A5, is an essential amino acid transporter that forms a heterodimeric complex with the glycoprotein cell-surface antigen heavy chain (4F2hc (CD98, SLC3A2)). Within nociceptive pathways, LAT1 is expressed in the dorsal root ganglia and spinal c...

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Bibliographic Details
Main Authors: Sascha R.A. Alles, Kimberly Gomez, Aubin Moutal, Rajesh Khanna
Format: Article
Language:English
Published: Elsevier 2020-08-01
Series:Neurobiology of Pain
Subjects:
LAT1
Inflammation
Neuropathic pain
mTOR
Ion channels
Gabapentinoids
Online Access:http://www.sciencedirect.com/science/article/pii/S2452073X20300088

Internet

http://www.sciencedirect.com/science/article/pii/S2452073X20300088

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