Pulmonary Stretch and Lung Mechanotransduction: Implications for Progression in the Fibrotic Lung

Pulmonary Stretch and Lung Mechanotransduction: Implications for Progression in the Fibrotic Lung

Lung fibrosis results from the synergic interplay between regenerative deficits of the alveolar epithelium and dysregulated mechanisms of repair in response to alveolar and vascular damage, which is followed by progressive fibroblast and myofibroblast proliferation and excessive deposition of the ex...

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Bibliographic Details
Main Authors: Alessandro Marchioni, Roberto Tonelli, Stefania Cerri, Ivana Castaniere, Dario Andrisani, Filippo Gozzi, Giulia Bruzzi, Linda Manicardi, Antonio Moretti, Jacopo Demurtas, Serena Baroncini, Alessandro Andreani, Gaia Francesca Cappiello, Stefano Busani, Riccardo Fantini, Luca Tabbì, Anna Valeria Samarelli, Enrico Clini
Format: Article
Language:English
Published: MDPI AG 2021-06-01
Series:International Journal of Molecular Sciences
Subjects:
mechanical ventilation
lung fibrosis
stress
strain
lung elastance
lung compliance
Online Access:https://www.mdpi.com/1422-0067/22/12/6443

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https://www.mdpi.com/1422-0067/22/12/6443

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