Gene Network Construction from Microarray Data Identifies a Key Network Module and Several Candidate Hub Genes in Age-Associated Spatial Learning Impairment

Gene Network Construction from Microarray Data Identifies a Key Network Module and Several Candidate Hub Genes in Age-Associated Spatial Learning Impairment

As humans age many suffer from a decrease in normal brain functions including spatial learning impairments. This study aimed to better understand the molecular mechanisms in age-associated spatial learning impairment (ASLI). We used a mathematical modeling approach implemented in Weighted Gene Co-ex...

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Bibliographic Details
Main Authors: Raihan Uddin, Shiva M. Singh
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-10-01
Series:Frontiers in Systems Neuroscience
Subjects:
microarray
spatial learning
learning impairment
brains
data integration
mathematical modeling
Online Access:http://journal.frontiersin.org/article/10.3389/fnsys.2017.00075/full

Internet

http://journal.frontiersin.org/article/10.3389/fnsys.2017.00075/full

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