CD4+ T Cells Orchestrate Lethal Immune Pathology despite Fungal Clearance during Cryptococcus neoformans Meningoencephalitis

CD4+ T Cells Orchestrate Lethal Immune Pathology despite Fungal Clearance during Cryptococcus neoformans Meningoencephalitis

Cryptococcus neoformans is a major fungal pathogen that disseminates to the central nervous system (CNS) to cause fatal meningoencephalitis, but little is known about immune responses within this immune-privileged site. CD4+ T cells have demonstrated roles in anticryptococcal defenses, but increasin...

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Bibliographic Details
Main Authors: Lori M. Neal, Enze Xing, Jintao Xu, Jessica L. Kolbe, John J. Osterholzer, Benjamin M. Segal, Peter R. Williamson, Michal A. Olszewski, Francoise Dromer
Format: Article
Language:English
Published: American Society for Microbiology 2017-11-01
Series:mBio
Online Access:http://mbio.asm.org/cgi/content/full/8/6/e01415-17

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http://mbio.asm.org/cgi/content/full/8/6/e01415-17

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