Detrimental effects of RNAi: a cautionary note on its use in Drosophila ageing studies.

RNA interference (RNAi) provides an important tool for gene function discovery. It has been widely exploited in Caenorhabditis elegans ageing research because it does not appear to have any non-specific effects on ageing-related traits in that model organism. We show here that ubiquitous, adult-onse...

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Bibliographic Details
Main Authors: Nazif Alic, Matthew P Hoddinott, Andrea Foley, Cathy Slack, Matthew D W Piper, Linda Partridge
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3444450?pdf=render