Biomimetic extracellular matrix coatings improve the chronic biocompatibility of microfabricated subdural microelectrode arrays.

Biomimetic extracellular matrix coatings improve the chronic biocompatibility of microfabricated subdural microelectrode arrays.

Intracranial electrodes are a vital component of implantable neurodevices, both for acute diagnostics and chronic treatment with open and closed-loop neuromodulation. Their performance is hampered by acute implantation trauma and chronic inflammation in response to implanted materials and mechanical...

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Bibliographic Details
Main Authors: Flavia Vitale, Wendy Shen, Nicolette Driscoll, Justin C Burrell, Andrew G Richardson, Oladayo Adewole, Brendan Murphy, Akshay Ananthakrishnan, Hanju Oh, Theodore Wang, Timothy H Lucas, D Kacy Cullen, Mark G Allen, Brian Litt
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC6211660?pdf=render

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http://europepmc.org/articles/PMC6211660?pdf=render

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