Assembly of Influenza hemagglutinin fusion peptide trimers in a phospholipid bilayer by coarse-grained simulations.
Membrane fusion is critical to eukaryotic cellular function and crucial to the entry of enveloped viruses such as influenza and human immunodeficiency virus. Influenza viral entry in the host cell is mediated by a 20-23 amino acid long sequence, called the fusion peptide (FP). Recently, possible str...
Main Authors: | Francesca eCollu, Enrico eSpiga, Christian Douglas Lorenz, Franca eFraternali |
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Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2015-11-01
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Series: | Frontiers in Molecular Biosciences |
Subjects: | |
Online Access: | http://journal.frontiersin.org/Journal/10.3389/fmolb.2015.00066/full |
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