Assembly of Influenza hemagglutinin fusion peptide trimers in a phospholipid bilayer by coarse-grained simulations.

Assembly of Influenza hemagglutinin fusion peptide trimers in a phospholipid bilayer by coarse-grained simulations.

Membrane fusion is critical to eukaryotic cellular function and crucial to the entry of enveloped viruses such as influenza and human immunodeficiency virus. Influenza viral entry in the host cell is mediated by a 20-23 amino acid long sequence, called the fusion peptide (FP). Recently, possible str...

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Bibliographic Details
Main Authors: Francesca eCollu, Enrico eSpiga, Christian Douglas Lorenz, Franca eFraternali
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-11-01
Series:Frontiers in Molecular Biosciences
Subjects:
Assembly
Molecular dynamic simulations
Phospholipid bilayer
theoretical investigation
Influenza Fusion Peptides
Coarse Grained Simulations
Online Access:http://journal.frontiersin.org/Journal/10.3389/fmolb.2015.00066/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fmolb.2015.00066/full

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