Resveratrol ameliorates renal damage, increases expression of heme oxygenase-1, and has anti-complement, anti-oxidative, and anti-apoptotic effects in a murine model of membranous nephropathy.

Resveratrol ameliorates renal damage, increases expression of heme oxygenase-1, and has anti-complement, anti-oxidative, and anti-apoptotic effects in a murine model of membranous nephropathy.

Idiopathic membranous nephropathy (MN) is an autoimmune-mediated glomerulonephritis and a common cause of nephrotic syndrome in adults. There are limited available treatments for MN. We assessed the efficacy of resveratrol (RSV) therapy for treatment of MN in a murine model of this disease.Murine MN...

Full description

Bibliographic Details
Main Authors: Chia-Chao Wu, Yen-Sung Huang, Jin-Shuen Chen, Ching-Feng Huang, Sui-Lung Su, Kuo-Cheng Lu, Yuh-Feng Lin, Pauling Chu, Shih-Hua Lin, Huey-Kang Sytwu
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4425525?pdf=render

Internet

http://europepmc.org/articles/PMC4425525?pdf=render

Similar Items