Trastuzumab Sensitizes Ovarian Cancer Cells to EGFR-targeted Therapeutics

<p>Abstract</p> <p>Background</p> <p>Early studies have demonstrated comparable levels of HER2/ErbB2 expression in both breast and ovarian cancer. Trastuzumab (Herceptin), a therapeutic monoclonal antibody directed against HER2, is FDA-approved for the treatment of both...

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Bibliographic Details
Main Authors: Wilken Jason A, Webster Kristy T, Maihle Nita J
Format: Article
Language:English
Published: BMC 2010-03-01
Series:Journal of Ovarian Research
Online Access:http://www.ovarianresearch.com/content/3/1/7