A Homogeneous Polysaccharide from Fructus Schisandra chinensis (Turz.) Baill Induces Mitochondrial Apoptosis through the Hsp90/AKT Signalling Pathway in HepG2 Cells

A Homogeneous Polysaccharide from Fructus Schisandra chinensis (Turz.) Baill Induces Mitochondrial Apoptosis through the Hsp90/AKT Signalling Pathway in HepG2 Cells

According to the potential anti-hepatoma therapeutic effect of Schisandra chinensis polysaccharides presented in previous studies, a bioactive constituent, homogeneous Schisandra chinensis polysaccharide-0-1 (SCP-0-1), molecular weight (MW) circa 69.980 kDa, was isolated and purified. We assessed th...

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Bibliographic Details
Main Authors: Yonglin Chen, Songshan Shi, Huijun Wang, Ning Li, Juan Su, Guixin Chou, Shunchun Wang
Format: Article
Language:English
Published: MDPI AG 2016-06-01
Series:International Journal of Molecular Sciences
Subjects:
hepatocellular carcinoma
Schisandra chinensis
polysaccharide
mitochondrial apoptosis
autophagy
Hsp90/AKT signalling pathway
Online Access:http://www.mdpi.com/1422-0067/17/7/1015

Internet

http://www.mdpi.com/1422-0067/17/7/1015

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