Impaired Dendritic Expression and Plasticity of h-Channels in the fmr1−/y Mouse Model of Fragile X Syndrome

Despite extensive research into both synaptic and morphological changes, surprisingly little is known about dendritic function in fragile X syndrome (FXS). We found that the dendritic input resistance of CA1 neurons was significantly lower in fmr1−/y versus wild-type mice. Consistent with elevated...

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Bibliographic Details
Main Authors: Darrin H. Brager, Arvin R. Akhavan, Daniel Johnston
Format: Article
Language:English
Published: Elsevier 2012-03-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124712000459