Saturated but not mono-unsaturated fatty acids induce apoptotic cell death in neonatal rat ventricular myocytes

The energy need of cardiac muscle cells in vivo is largely covered by the oxidation of saturated and mono-unsaturated fatty acids (FA). However, in vitro studies have shown that the saturated FA C16:0 at physiological concentrations exerts detrimental effects on primary cultures of neonatal rat vent...

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Bibliographic Details
Main Authors: J E de Vries, M M Vork, T H Roemen, Y F de Jong, J P Cleutjens, G J van der Vusse, M van Bilsen
Format: Article
Language:English
Published: Elsevier 1997-07-01
Series:Journal of Lipid Research
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520374216