Vpu-dependent block to incorporation of GaLV Env into lentiviral vectors

<p>Abstract</p> <p>Background</p> <p>The gibbon ape leukemia virus (GaLV) Env protein mediates entry into a wide range of human cells and is frequently used to pseudotype retroviral vectors. However, an incompatibility exists between GaLV Env and lentiviral vectors that...

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Bibliographic Details
Main Authors: Cannon Paula M, Oldenburg Jill E, Droniou-Bonzom Magali E, Christodoulopoulos Ilias
Format: Article
Language:English
Published: BMC 2010-01-01
Series:Retrovirology
Online Access:http://www.retrovirology.com/content/7/1/4