Bioengineering of functional human induced pluripotent stem cell-derived intestinal grafts

Bioengineering of functional human induced pluripotent stem cell-derived intestinal grafts

There is a need for humanised grafts to treat patients with intestinal failure. Here, the authors generate intestinal grafts by recellularizing native intestinal matrix with human induced pluripotent stem cell-derived epithelium and human endothelium, and show nutrient absorption after transplantati...

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Bibliographic Details
Main Authors: Kentaro Kitano, Dana M. Schwartz, Haiyang Zhou, Sarah E. Gilpin, Gregory R. Wojtkiewicz, Xi Ren, Cesar A. Sommer, Amalia V. Capilla, Douglas J. Mathisen, Allan M. Goldstein, Gustavo Mostoslavsky, Harald C. Ott
Format: Article
Language:English
Published: Nature Publishing Group 2017-10-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-017-00779-y

Internet

https://doi.org/10.1038/s41467-017-00779-y

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