Lactate as a metabolite from probiotic Lactobacilli mitigates ethanol-induced gastric mucosal injury: an in vivo study

Lactate as a metabolite from probiotic Lactobacilli mitigates ethanol-induced gastric mucosal injury: an in vivo study

Abstract Background Pre-administration of probiotic Lactobacilli attenuates ethanol-induced gastric mucosal injury (GMI). The underpinning mechanisms remain to be elucidated. We speculated that lactate, the main metabolite of Lactobacillus that can be safely used as a common food additive, mediated...

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Bibliographic Details
Main Authors: Yingpeng Huang, Jiali Zhang, Renjie Dong, Xiawei Ji, Yusha Jiang, Jianke Cen, Zhihuai Bai, Kairui Hong, Huihui Li, Jiajing Chen, Jinhui Zhou, Fanyu Qian, Fangyan Wang, Yue Qu, Yan Zhou
Format: Article
Language:English
Published: BMC 2021-01-01
Series:BMC Complementary Medicine and Therapies
Subjects:
Lactate
Ethanol
Gastric mucosal injury
Inflammation
Apoptosis
Tight junction proteins
Online Access:https://doi.org/10.1186/s12906-020-03198-7

Internet

https://doi.org/10.1186/s12906-020-03198-7

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