Vector-borne transmission imposes a severe bottleneck on an RNA virus population.

RNA viruses typically occur in genetically diverse populations due to their error-prone genome replication. Genetic diversity is thought to be important in allowing RNA viruses to explore sequence space, facilitating adaptation to changing environments and hosts. Some arboviruses that infect both a...

Full description

Bibliographic Details
Main Authors: Naomi L Forrester, Mathilde Guerbois, Robert L Seymour, Heidi Spratt, Scott C Weaver
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-09-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC3441635?pdf=render