Glucocorticoids Decrease Astrocyte Numbers by Reducing Glucocorticoid Receptor Expression In Vitro and In Vivo

Glucocorticoids are stress hormones released from the adrenal cortex and their concentration is controlled by the hypothalamic–pituitary–adrenal axis. In this study, we investigated the effect of glucocorticoids on the number of astrocytes and glucocorticoid receptor (GR) expression in vitro and in...

Full description

Bibliographic Details
Main Authors: Kazuhiro Unemura, Toshiaki Kume, Minami Kondo, Yuki Maeda, Yasuhiko Izumi, Akinori Akaike
Format: Article
Language:English
Published: Elsevier 2012-01-01
Series:Journal of Pharmacological Sciences
Online Access:http://www.sciencedirect.com/science/article/pii/S1347861319305213