Development of different degrees of elastase-induced emphysema in mice: a randomized controlled experimental studyenfisema pulmonar, mecânica pulmonar, elastase pancreática.

Development of different degrees of elastase-induced emphysema in mice: a randomized controlled experimental studyenfisema pulmonar, mecânica pulmonar, elastase pancreática.

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Introduction: Mouse models of emphysema are important tools for testing different therapeutic strategies. The aim of this study was to develop a mouse model of emphysema induced by different doses of elastase in order to produce different degrees of severity. Methods: Thirty female mice (C57BL/6) w...

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Bibliographic Details
Main Authors: Cristiana Palma Kuhl, Tuane Nerissa Alves Garcez, Alessandra Bileski Magrisso, Claudia Cilene Fernandes Correia Laurino, Elizabeth Obino Cirne-Lima, Patricia Rieken Macedo Rocco, Amarilio Vieira de Macedo Neto
Format: Article
Language:English
Published: Hospital de Clinicas de Porto Alegre ; Universidade Federal do Rio Grande do Sul (UFRGS) 2014-10-01
Series:Clinical and Biomedical Research
Subjects:
Pulmonary emphysema
Lung mechanics
Pancreatic elastase.
Online Access:http://seer.ufrgs.br/index.php/hcpa/article/view/48676

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http://seer.ufrgs.br/index.php/hcpa/article/view/48676

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