Tailoring crystal size distributions for product performance, compaction of paracetamol

Tailoring crystal size distributions for product performance, compaction of paracetamol

Paracetamol crystals often exhibit poor compressibility properties, which results in capping issues. The Particle Size Distribution (PSD) of paracetamol was engineered to improve the compressibility of paracetamol crystals. This was accomplished by growing paracetamol crystals in the presence of add...

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Bibliographic Details
Main Authors: Leila Keshavarz, Mahboubeh Pishnamazi, U.B. Rao Khandavilli, Saeed Shirazian, Maurice N. Collins, Gavin M. Walker, Patrick J. Frawley
Format: Article
Language:English
Published: Elsevier 2021-04-01
Series:Arabian Journal of Chemistry
Subjects:
Pharmaceutics
Crystallization
Paracetamol
Particle size distribution
Additives
Compressibility
Online Access:http://www.sciencedirect.com/science/article/pii/S1878535221001040

Internet

http://www.sciencedirect.com/science/article/pii/S1878535221001040

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