What renders TAU toxic
TAU is a microtubule-associated protein that under pathological conditions such as Alzheimer’s disease forms insoluble, filamentous aggregates. When twenty years after TAU’s discovery the first TAU transgenic mouse models were established, one declared goal that was achieved was the modelling of aut...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Frontiers Media S.A.
2013-06-01
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| Series: | Frontiers in Neurology |
| Subjects: | |
| Online Access: | http://journal.frontiersin.org/Journal/10.3389/fneur.2013.00072/full |