Molecular mechanisms of detection and discrimination of dynamic signals

Abstract Many molecules decode not only the concentration of cellular signals, but also their temporal dynamics. However, little is known about the mechanisms that underlie the detection and discrimination of dynamic signals. We used computational modelling of the interaction of a ligand with multip...

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Bibliographic Details
Main Authors: G. Antunes, A. C. Roque, F. M. Simoes-de-Souza
Format: Article
Language:English
Published: Nature Publishing Group 2018-02-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-018-20842-y