Resveratrol modulates the inflammatory response via an estrogen receptor-signal integration network

Resveratrol modulates the inflammatory response via an estrogen receptor-signal integration network

Resveratrol has beneficial effects on aging, inflammation and metabolism, which are thought to result from activation of the lysine deacetylase, sirtuin 1 (SIRT1), the cAMP pathway, or AMP-activated protein kinase. In this study, we report that resveratrol acts as a pathway-selective estrogen recept...

Full description

Bibliographic Details
Main Authors: Jerome C Nwachukwu, Sathish Srinivasan, Nelson E Bruno, Alexander A Parent, Travis S Hughes, Julie A Pollock, Olsi Gjyshi, Valerie Cavett, Jason Nowak, Ruben D Garcia-Ordonez, René Houtman, Patrick R Griffin, Douglas J Kojetin, John A Katzenellenbogen, Michael D Conkright, Kendall W Nettles
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2014-04-01
Series:eLife
Subjects:
resveratrol
estrogen receptor
inflammation
x-ray crystallography
transcription regulation
Online Access:https://elifesciences.org/articles/02057

Internet

https://elifesciences.org/articles/02057

Similar Items