Deconvolution of Complex 1D NMR Spectra Using Objective Model Selection.

by Travis S Hughes, Henry D Wilson, Ian Mitchelle S de Vera, Douglas J Kojetin
Published 2015-01-01

Cooperative cobinding of synthetic and natural ligands to the nuclear receptor PPARγ

by Jinsai Shang, Richard Brust, Sarah A Mosure, Jared Bass, Paola Munoz-Tello, Hua Lin, Travis S Hughes, Miru Tang, Qingfeng Ge, Theodore M Kamenekca, Douglas J Kojetin
Published 2018-12-01

Definition of functionally and structurally distinct repressive states in the nuclear receptor PPARγ

by Zahra Heidari, Ian M. Chrisman, Michelle D. Nemetchek, Scott J. Novick, Anne-Laure Blayo, Trey Patton, Desiree E. Mendes, Philippe Diaz, Theodore M. Kamenecka, Patrick R. Griffin, Travis S. Hughes
Published 2019-12-01

A Literature-Derived Knowledge Graph Augments the Interpretation of Single Cell RNA-seq Datasets

by Deeksha Doddahonnaiah, Patrick J. Lenehan, Travis K. Hughes, David Zemmour, Enrique Garcia-Rivera, A. J. Venkatakrishnan, Ramakrishna Chilaka, Apoorv Khare, Akhil Kasaraneni, Abhinav Garg, Akash Anand, Rakesh Barve, Viswanathan Thiagarajan, Venky Soundararajan
Published 2021-06-01

A structural mechanism for directing corepressor-selective inverse agonism of PPARγ

by Richard Brust, Jinsai Shang, Jakob Fuhrmann, Sarah A. Mosure, Jared Bass, Andrew Cano, Zahra Heidari, Ian M. Chrisman, Michelle D. Nemetchek, Anne-Laure Blayo, Patrick R. Griffin, Theodore M. Kamenecka, Travis S. Hughes, Douglas J. Kojetin
Published 2018-11-01

Defining a conformational ensemble that directs activation of PPARγ

by Ian M. Chrisman, Michelle D. Nemetchek, Ian Mitchelle S. de Vera, Jinsai Shang, Zahra Heidari, Yanan Long, Hermes Reyes-Caballero, Rodrigo Galindo-Murillo, Thomas E. Cheatham, Anne-Laure Blayo, Youseung Shin, Jakob Fuhrmann, Patrick R. Griffin, Theodore M. Kamenecka, Douglas J. Kojetin, Travis S. Hughes
Published 2018-05-01

Resveratrol modulates the inflammatory response via an estrogen receptor-signal integration network

by Jerome C Nwachukwu, Sathish Srinivasan, Nelson E Bruno, Alexander A Parent, Travis S Hughes, Julie A Pollock, Olsi Gjyshi, Valerie Cavett, Jason Nowak, Ruben D Garcia-Ordonez, René Houtman, Patrick R Griffin, Douglas J Kojetin, John A Katzenellenbogen, Michael D Conkright, Kendall W Nettles
Published 2014-04-01

Harnessing single-cell genomics to improve the physiological fidelity of organoid-derived cell types

by Benjamin E. Mead, Jose Ordovas-Montanes, Alexandra P. Braun, Lauren E. Levy, Prerna Bhargava, Matthew J. Szucs, Dustin A. Ammendolia, Melanie A. MacMullan, Xiaolei Yin, Travis K. Hughes, Marc H. Wadsworth, Rushdy Ahmad, Seth Rakoff-Nahoum, Steven A. Carr, Robert Langer, James J. Collins, Alex K. Shalek, Jeffrey M. Karp
Published 2018-06-01