High Concentration of C5a-Induced Mitochondria-Dependent Apoptosis in Murine Kidney Endothelial Cells

Patients with a relapse of idiopathic nephrotic syndrome have significantly increased levels of serum complement component 5a (C5a), and proteinuria has been noted in mice treated with C5a via changes in permeability of kidney endothelial cells (KECs) in established animal models. However, the apopt...

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Bibliographic Details
Main Authors: I-Jung Tsai, Wei-Chou Lin, Yao-Hsu Yang, Yu-Lin Tseng, Yen-Hung Lin, Chia-Hung Chou, Yong-Kwei Tsau
Format: Article
Language:English
Published: MDPI AG 2019-09-01
Series:International Journal of Molecular Sciences
Subjects:
C5a
Online Access:https://www.mdpi.com/1422-0067/20/18/4465