Genetic variation of the serotonin 2a receptor affects hippocampal novelty processing in humans.

Serotonin (5-hydroxytryptamine, 5-HT) is an important neuromodulator in learning and memory processes. A functional genetic polymorphism of the 5-HT 2a receptor (5-HTR2a His452Tyr), which leads to blunted intracellular signaling, has previously been associated with explicit memory performance in sev...

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Main Authors: Björn H Schott, Constanze I Seidenbecher, Sylvia Richter, Torsten Wüstenberg, Grazyna Debska-Vielhaber, Heike Schubert, Hans-Jochen Heinze, Alan Richardson-Klavehn, Emrah Düzel
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3022731?pdf=render