Extracellular cyclophilin-A stimulates ERK1/2 phosphorylation in a cell-dependent manner but broadly stimulates nuclear factor kappa B
<p>Abstract</p> <p>Background</p> <p>Although the peptidyl-prolyl isomerase, cyclophilin-A (peptidyl-prolyl isomerase, PPIA), has been studied for decades in the context of its intracellular functions, its extracellular roles as a major contributor to both inflammation...
Main Authors: | Bahmed Karim, Henry Curtis, Holliday Michael, Redzic Jasmina, Ciobanu Madalina, Zhang Fengli, Weekes Colin, Sclafani Robert, DeGregori James, Eisenmesser Elan |
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Format: | Article |
Language: | English |
Published: |
BMC
2012-07-01
|
Series: | Cancer Cell International |
Subjects: |
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