Extracellular cyclophilin-A stimulates ERK1/2 phosphorylation in a cell-dependent manner but broadly stimulates nuclear factor kappa B

<p>Abstract</p> <p>Background</p> <p>Although the peptidyl-prolyl isomerase, cyclophilin-A (peptidyl-prolyl isomerase, PPIA), has been studied for decades in the context of its intracellular functions, its extracellular roles as a major contributor to both inflammation...

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Bibliographic Details
Main Authors: Bahmed Karim, Henry Curtis, Holliday Michael, Redzic Jasmina, Ciobanu Madalina, Zhang Fengli, Weekes Colin, Sclafani Robert, DeGregori James, Eisenmesser Elan
Format: Article
Language:English
Published: BMC 2012-07-01
Series:Cancer Cell International
Subjects:
BSG
MMP