Apoptosis induced by t10,c12-conjugated linoleic acid is mediated by an atypical endoplasmic reticulum stress response*

Conjugated linoleic acid (CLA) inhibits rat mammary carcinogenesis, in part by inducing apoptosis of preneoplastic and neoplastic mammary epithelial cells. The current study focused on the mechanism by which apoptosis is induced. In TM4t mammary tumor cells, trans-10,cis-12 (t10,c12)-CLA induced pro...

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Bibliographic Details
Main Authors: Lihui Ou, Yue Wu, Clement Ip, Xiaojing Meng, Yung-Chun Hsu, Margot M. Ip
Format: Article
Language:English
Published: Elsevier 2008-05-01
Series:Journal of Lipid Research
Subjects:
CLA
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520425854