Cryptopleurine analogs with modification of e ring exhibit different mechanism to rac-cryptopleurine and tylophorine.

Tylophorine analogs exhibit a broad range of pharmacological activities, including anti-cancer, anti-inflammatory, anti-autoimmune, and anti-virus effects. Structure-activity relationship study of different structure tylophorine analogs can provide further understanding of their biological activity....

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Bibliographic Details
Main Authors: Ying Wang, Hui-Chyn Wong, Elizabeth A Gullen, Wing Lam, Xiaoming Yang, Qian Shi, Kuo-Hsiung Lee, Yung-Chi Cheng
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3519526?pdf=render