Genomic Instability: The Driving Force behind Refractory/Relapsing Hodgkin’s Lymphoma

Genomic Instability: The Driving Force behind Refractory/Relapsing Hodgkin’s Lymphoma

In classical Hodgkin’s lymphoma (HL) the malignant mononuclear Hodgkin (H) and multinuclear, diagnostic Reed-Sternberg (RS) cells are rare and generally make up <3% of the total cellular mass of the affected lymph nodes. During recent years, the introduction of laser micro-dissection techniques a...

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Bibliographic Details
Main Authors: Sabine Mai, Christiaan Righolt, Hans Knecht
Format: Article
Language:English
Published: MDPI AG 2013-06-01
Series:Cancers
Subjects:
Hodgkin’s lymphoma
Reed-Sternberg cell
telomere
shelterin
3D-FISH
nuclear architecture
genomic instability
nano-morphology
Online Access:http://www.mdpi.com/2072-6694/5/2/714

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http://www.mdpi.com/2072-6694/5/2/714

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