Hidden pharmacological activities of valproic acid: A new insight

Hidden pharmacological activities of valproic acid: A new insight

Valproic acid (VPA) is an approved drug for managing epileptic seizures, bipolar disorders, and migraine. VPA has been shown to elevate the level of gamma-aminobutyric acid (GABA) in the brain through competitive inhibition of GABA transaminase, thus promoting the availability of synaptic GABA and f...

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Bibliographic Details
Main Authors: Dhirendra Singh, Sumeet Gupta, Inderjeet Verma, Mohamed A. Morsy, Anroop B. Nair, Al-Shaimaa F. Ahmed
Format: Article
Language:English
Published: Elsevier 2021-10-01
Series:Biomedicine & Pharmacotherapy
Subjects:
Valproic acid
Histone deacetylases
Diabetes mellitus
Renal protection
Cardiac remodeling
Muscular dystrophy
Online Access:http://www.sciencedirect.com/science/article/pii/S0753332221008040

Internet

http://www.sciencedirect.com/science/article/pii/S0753332221008040

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