Diminished ketone interconversion, hepatic TCA cycle flux, and glucose production in D-β-hydroxybutyrate dehydrogenase hepatocyte-deficient mice
Objective: Throughout the last decade, interest has intensified in intermittent fasting, ketogenic diets, and exogenous ketone therapies as prospective health-promoting, therapeutic, and performance-enhancing agents. However, the regulatory roles of ketogenesis and ketone metabolism on liver homeost...
Main Authors: | David B. Stagg, Jacob R. Gillingham, Alisa B. Nelson, Justin E. Lengfeld, D. André d’Avignon, Patrycja Puchalska, Peter A. Crawford |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2021-11-01
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Series: | Molecular Metabolism |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2212877821001149 |
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